File:Serpin mechanism.png
Size of this preview: ༧༢༥ × ༥༩༩ pixels. Other resolutions: ༢༩༠ × ༢༤༠ pixels | ༥༨༡ × ༤༨༠ pixels | ༩༢༩ × ༧༦༨ pixels | ༡,༢༣༩ × ༡,༠༢༤ pixels | ༡,༨༠༠ × ༡,༤༨༨ pixels.
ཐོག་མའི་ཡིག་ཆ། (༡,༨༠༠ × ༡,༤༨༨ བརྙན་རྒྱུ།, ཡིག་ཆ་ཆེ་ཆུང།: ༥༡༣ KB, རྣམ་གཞག།: image/png)
བསྡུས་དོན།
| Description |
English: Serine proteases operate by a two-step catalytic mechanism. First, the substrate (blue) is attacked by the catalytic triad (red) to form an acyl-enzyme intermediate. The intermediate is typically resolved by hydrolysis by water. However, when the reactive centre loop (RCL) of a serpin is attacked, the conformational change (blue arrow) pulls the catalytic triad out of position, preventing it from completing catalysis. (Based on PDB: 1K9O, 1EZX) |
| Date | |
| Source | Own work |
| Author | Thomas Shafee |
གན་རྒྱ་ནང་ཞུགས་པ།
I, the copyright holder of this work, hereby publish it under the following license:
This file is licensed under the Creative Commons Attribution 4.0 International license.
- You are free:
- to share – to copy, distribute and transmit the work
- to remix – to adapt the work
- Under the following conditions:
- attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
ཡིག་ཆའི་ལོ་རྒྱུས།
ཟླ་ཚེས་/དུས་ཚོད་གནུན་ཏེ་རྩོམ་ཡིག་ལ་ལྟ་བ།
| ཚེས་གྲངས། / དུས་ཚོད། | བསྡུས་དོན། | ཚད། | སྤྱོད་མི། | བསམ་ཚུལ། | |
|---|---|---|---|---|---|
| ད་ལྟ། | ༠༩:༥༦, ༢༢ ཟླ་བཅུ་གཉིས་པ། ༢༠༡༥ | | ༡,༨༠༠ × ༡,༤༨༨ (༥༡༣ KB) | Evolution and evolvability | Higher resolution |
| ༠༥:༡༩, ༡༩ ཟླ་བཅུ་གཉིས་པ། ༢༠༡༥ |  | ༡,༣༦༢ × ༡,༡༢༦ (༣༠༠ KB) | Evolution and evolvability | Minor arrow correction | |
| ༠༥:༠༨, ༡༩ ཟླ་བཅུ་གཉིས་པ། ༢༠༡༥ |  | ༡,༣༦༢ × ༡,༡༢༦ (༣༠༠ KB) | Evolution and evolvability | added arrow and removed transparency | |
| ༠༥:༠༤, ༡༩ ཟླ་བཅུ་གཉིས་པ། ༢༠༡༥ |  | ༡,༣༦༢ × ༡,༡༡༤ (༣༦༠ KB) | Evolution and evolvability | Cross-wiki upload from en.wikipedia.org |
ཡིག་ཆ་བེད་སྤྱོད་ཁུལ།
There are no pages that use this file.
Global file usage
The following other wikis use this file:
