File:Serpin equilibrium.png
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ཐོག་མའི་ཡིག་ཆ། (༣,༠༠༠ × ༡,༩༠༢ བརྙན་རྒྱུ།, ཡིག་ཆ་ཆེ་ཆུང།: ༡.༤༡ MB, རྣམ་གཞག།: image/png)
བསྡུས་དོན།
| Description |
English: The native state of serpins is an equilibrium between a fully-stressed state (left) and a partially relaxed state (right). The five-stranded A-sheet (light blue) contains two functionally important regions for the serpin's mechanism, the breach and the shutter. The Reactive Centre Loop (RCL, blue) exists in a dynamic equilibrium between the fully exposed conformation (left) and a conformation where it is partially inserted into the breach of the A-sheet (right). (PDB: 1QLP, 1YXA).
[1] [2] |
| Date | |
| Source | Own work |
| Author | Thomas Shafee |
གན་རྒྱ་ནང་ཞུགས་པ།
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- ↑ Elliott PR, Lomas DA, Carrell RW, Abrahams JP. (1996). "Inhibitory conformation of the reactive loop of alpha 1-antitrypsin". Nature Structural & Molecular Biology 3 (8): 676–81. DOI:10.1038/nsb0896-676. PMID 8756325.
- ↑ (2005). "The murine orthologue of human antichymotrypsin: a structural paradigm for clade A3 serpins.". J Biol Chem 280 (52): 43168–78. DOI:10.1074/jbc.M505598200. PMID 16141197.
ཡིག་ཆའི་ལོ་རྒྱུས།
ཟླ་ཚེས་/དུས་ཚོད་གནུན་ཏེ་རྩོམ་ཡིག་ལ་ལྟ་བ།
| ཚེས་གྲངས། / དུས་ཚོད། | བསྡུས་དོན། | ཚད། | སྤྱོད་མི། | བསམ་ཚུལ། | |
|---|---|---|---|---|---|
| ད་ལྟ། | ༢༣:༢༣, ༦ ཟླ་བཅུ་བ། ༢༠༡༦ | | ༣,༠༠༠ × ༡,༩༠༢ (༡.༤༡ MB) | Cmdrjameson | Compressed with pngout. Reduced by 772kB (34% decrease). |
| ༢༣:༠༥, ༡༩ ཟླ་གསུམ། ༢༠༡༦ |  | ༣,༠༠༠ × ༡,༩༠༢ (༢.༡༦ MB) | Evolution and evolvability | Colour tweaks | |
| ༡༢:༠༥, ༡༤ ཟླ་བཅུ་གཉིས་པ། ༢༠༡༥ |  | ༡,༢༤༦ × ༧༦༥ (༤༧༦ KB) | Evolution and evolvability | Cross-wiki upload from en.wikipedia.org |
ཡིག་ཆ་བེད་སྤྱོད་ཁུལ།
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